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FKBP5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

FKBP5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721216
  • Target See all FKBP5 Proteins
    FKBP5 (FK506 Binding Protein 5 (FKBP5))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FKBP5 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human FKBP5 / FKBP51 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FKBP5 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FKBP5 (FK506 Binding Protein 5 (FKBP5))
    Alternative Name
    Fkbp5,fkbp51 (FKBP5 Products)
    Synonyms
    FKBP5 Protein, FKBP-5 Protein, AIG6 Protein, FKBP51 Protein, FKBP54 Protein, P54 Protein, PPIase Protein, Ptg-10 Protein, D17Ertd592e Protein, Dit1 Protein, si:zc263a23.8 Protein, wu:fc31g11 Protein, wu:fl87b03 Protein, zgc:64082 Protein, FK506 binding protein 5 Protein, FKBP5 Protein, fkbp5 Protein, Fkbp5 Protein
    Background
    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
    Molecular Weight
    51 kDa
    NCBI Accession
    NP_004108
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