FNIP2 Protein (Myc-DYKDDDDK Tag)
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- Target See all FNIP2 Proteins
- FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FNIP2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FNIP2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FNIP2 Protein
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Folliculin Interacting Protein 2 (FNIP2) (AA 1-1114) protein (Strep Tag)
Crystallography grade FNIP2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Folliculin Interacting Protein 2 (FNIP2) (AA 1-1108) protein (Strep Tag)Crystallography grade FNIP2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
- Alternative Name
- Fnip2 (FNIP2 Products)
- Synonyms
- LOC797213 Protein, FNIPL Protein, MAPO1 Protein, D630023B12Rik Protein, mKIAA1450 Protein, RGD1562174 Protein, folliculin interacting protein 2 Protein, si:ch211-42i9.8 Protein, FNIP2 Protein, si:ch211-42i9.8 Protein, fnip2 Protein, Fnip2 Protein
- Background
- This gene encodes a member of the folliculin-interacting protein family. The encoded protein binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK) and be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This protein may also play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. A homologous binding partner of this protein, folliculin-interacting protein 1, has similar binding activities and may suggest functional redundancy within this protein family. Both folliculin-interacting proteins have also been shown to bind the molecular chaperone heat shock protein-90 (Hsp90) and they may function as a co-chaperones in the stabilization of tumor suppressor folliculin which is a target of Hsp90 chaperone activity.
- Molecular Weight
- 121.9 kDa
- NCBI Accession
- NP_065891
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