FTO Protein (Myc-DYKDDDDK Tag)
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- Target See all FTO Proteins
- FTO (Fat Mass and Obesity-Associated (FTO))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FTO protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human FTO protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FTO Protein
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Fat Mass and Obesity-Associated (FTO) (AA 1-139) protein (GST tag)
FTO Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Fat Mass and Obesity-Associated (FTO) (AA 1-505) protein (Strep Tag)Crystallography grade FTO Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Fat Mass and Obesity-Associated (FTO) (AA 1-502) protein (Strep Tag)Crystallography grade FTO Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FTO (Fat Mass and Obesity-Associated (FTO))
- Alternative Name
- Fto (FTO Products)
- Synonyms
- AW743446 Protein, mKIAA1752 Protein, RGD1305121 Protein, FTO, alpha-ketoglutarate dependent dioxygenase Protein, fat mass and obesity associated Protein, fat mass and obesity associated L homeolog Protein, FTO Protein, Fto Protein, fto.L Protein
- Background
- This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
- Molecular Weight
- 58.1 kDa
- NCBI Accession
- NP_001073901
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