GNA11 Protein (Myc-DYKDDDDK Tag)
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- Target See all GNA11 Proteins
- GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GNA11 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human G protein alpha 11 / GNA11 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GNA11 Protein
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Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) (AA 1-359) protein (GST tag)
GNA11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) (AA 1-359) protein (Strep Tag)Crystallography grade GNA11 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11) (AA 1-359) protein (Strep Tag)Crystallography grade GNA11 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))
- Alternative Name
- G Protein alpha 11,gna11 (GNA11 Products)
- Synonyms
- Dsk7 Protein, E430025L19 Protein, GNA-11 Protein, HHC2 Protein, HYPOC2 Protein, G-alpha-11 Protein, gna11 Protein, si:dkey-42p8.2 Protein, wu:fb12d06 Protein, zgc:101761 Protein, guanine nucleotide binding protein, alpha 11 Protein, G protein subunit alpha 11 Protein, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) Protein, guanine nucleotide regulatory protein G11 alpha subunit Protein, guanine nucleotide binding protein (G protein), alpha 11a (Gq class) Protein, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) S homeolog Protein, guanine nucleotide binding protein (G protein), alpha 11b (Gq class) Protein, Gna11 Protein, GNA11 Protein, gna11 Protein, gna11a Protein, gna11.S Protein, gna11b Protein
- Background
- The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.
- Molecular Weight
- 41.9 kDa
- NCBI Accession
- NP_002058
- Pathways
- G-protein mediated Events
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