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GAD Protein (Myc-DYKDDDDK Tag)

GAD1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721538
  • Target See all GAD (GAD1) Proteins
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    Protein Type
    Recombinant
    Origin
    • 5
    • 4
    • 3
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GAD protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human GAD1 / GAD67 (transcript variant GAD67) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GAD1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    Alternative Name
    Gad1,gad67 (GAD1 Products)
    Synonyms
    CPSQ1 Protein, GAD Protein, SCP Protein, GAD-67 Protein, cpsq1 Protein, gad1 Protein, gad1-A Protein, gad67 Protein, GAD67 Protein, GAD1 Protein, GLUTAMATE DECARBOXYLASE Protein, GLUTAMATE DECARBOXYLASE 1 Protein, MKP11.30 Protein, MKP11_30 Protein, glutamate decarboxylase Protein, EP10 Protein, GAD25 Protein, GAD44 Protein, Gad-1 Protein, Gad67 Protein, glutamate decarboxylase 1 Protein, glutamate decarboxylase 1 L homeolog Protein, glutamate decarboxylase Protein, glutamate decarboxylase 1b Protein, GAD1 Protein, gad1.1.L Protein, GAD Protein, Gad1 Protein, gad1b Protein
    Background
    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
    Molecular Weight
    66.7 kDa
    NCBI Accession
    NP_000808
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