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GEMIN8 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

GEMIN8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721806
  • Target See all GEMIN8 Proteins
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GEMIN8 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Gemin-8 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GEMIN8 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Alternative Name
    Gemin-8 (GEMIN8 Products)
    Synonyms
    FAM51A1 Protein, B130034M20Rik Protein, B930082C09Rik Protein, BC023488 Protein, gemin-8 Protein, gem nuclear organelle associated protein 8 Protein, gemin8 Protein, GEMIN8 Protein, Gemin8 Protein
    Background
    The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.
    Molecular Weight
    28.5 kDa
    NCBI Accession
    NP_060326
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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