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POLR2M Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

GRINL1A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2722004
  • Target See all POLR2M (GRINL1A) Proteins
    POLR2M (GRINL1A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Like 1A (GRINL1A))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This POLR2M protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GRINL1A Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Montesinos-Rongen, Purschke, Brunn, May, Nordhoff, Marcus, Deckert: "Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1312-9, (2015) (PubMed).

  • Target
    POLR2M (GRINL1A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Like 1A (GRINL1A))
    Abstract
    GRINL1A Products
    Synonyms
    GCOM1 Protein, GRINL1A Protein, Gdown Protein, Gdown1 Protein, AA407243 Protein, AA408799 Protein, AI303746 Protein, AW553238 Protein, D9Wsu138e Protein, Grinl1a Protein, mKIAA4185 Protein, Glurr Protein, RNA polymerase II subunit M Protein, polymerase (RNA) II (DNA directed) polypeptide M Protein, POLR2M Protein, Polr2m Protein
    Background
    This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4. Readthrough transcription between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein) is represented with GeneID 145781.
    Molecular Weight
    41.6 kDa
    NCBI Accession
    NP_056347
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