GTF2A1L Protein (His tag)

Catalog No. ABIN2722302

Product Details

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GTF2A1L protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human GTF2A1L / ALF (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Alternative Name: Gtf2a1l,alf (GTF2A1L Products)

Synonyms: ALF Protein, 1700011N16Rik Protein, Alf Protein, Gtf2a1lf Protein, general transcription factor IIA subunit 1 like Protein, general transcription factor IIA, 1-like Protein, general transcription factor 2A subunit 1 like Protein, GTF2A1L Protein, Gtf2a1l Protein

Background: The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Molecular Weight: 52.3 kDa

NCBI Accession: NP_006863