Hairless Protein (HR) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all Hairless (HR) Proteins
- Hairless (HR)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Hairless protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Hairless / HR (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HR Protein
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Hairless (HR) (AA 1090-1189) protein (GST tag)
HR Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Hairless (HR) (AA 1-1189) protein (Strep Tag)Crystallography grade HR Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Hairless (HR) (AA 1-1182) protein (His tag)Crystallography grade HR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Hairless (HR) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Hairless (HR)
- Alternative Name
- Hairless,hr (HR Products)
- Synonyms
- ALUNC Protein, AU Protein, HSA277165 Protein, MUHH Protein, MUHH1 Protein, HR Protein, N Protein, ba Protein, bldy Protein, hr Protein, rh Protein, rh-bmh Protein, rhino Protein, HR, lysine demethylase and nuclear receptor corepressor Protein, hairless Protein, HR Protein, Hr Protein
- Background
- This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 121.7 kDa
- NCBI Accession
- NP_060881
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