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HCK Protein (Myc-DYKDDDDK Tag)

HCK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2722464
  • Target See all HCK Proteins
    HCK (Hemopoietic Cell Kinase (HCK))
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This HCK protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human HCK protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HCK Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    HCK (Hemopoietic Cell Kinase (HCK))
    Alternative Name
    Hck (HCK Products)
    Synonyms
    laloo Protein, HCK Protein, MGC107870 Protein, JTK9 Protein, p59Hck Protein, p61Hck Protein, AI849071 Protein, Bmk Protein, Hctk Protein, p56Hck Protein, HCK proto-oncogene, Src family tyrosine kinase L homeolog Protein, HCK proto-oncogene, Src family tyrosine kinase Protein, hemopoietic cell kinase Protein, hck.L Protein, HCK Protein, hck Protein, Hck Protein
    Background
    The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
    Molecular Weight
    59.4 kDa
    NCBI Accession
    NP_002101
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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