HCK Protein (Myc-DYKDDDDK Tag)
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- Target See all HCK Proteins
- HCK (Hemopoietic Cell Kinase (HCK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HCK protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human HCK protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HCK Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HCK (Hemopoietic Cell Kinase (HCK))
- Alternative Name
- Hck (HCK Products)
- Synonyms
- laloo Protein, HCK Protein, MGC107870 Protein, JTK9 Protein, p59Hck Protein, p61Hck Protein, AI849071 Protein, Bmk Protein, Hctk Protein, p56Hck Protein, HCK proto-oncogene, Src family tyrosine kinase L homeolog Protein, HCK proto-oncogene, Src family tyrosine kinase Protein, hemopoietic cell kinase Protein, hck.L Protein, HCK Protein, hck Protein, Hck Protein
- Background
- The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
- Molecular Weight
- 59.4 kDa
- NCBI Accession
- NP_002101
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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