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HMBS Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

HMBS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2722852
  • Target See all HMBS Proteins
    HMBS (Hydroxymethylbilane Synthase (HMBS))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 7
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This HMBS protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human HMBS (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HMBS Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    HMBS (Hydroxymethylbilane Synthase (HMBS))
    Alternative Name
    Hmbs (HMBS Products)
    Synonyms
    PBG-D Protein, PBGD Protein, PORC Protein, UPS Protein, URO-S Protein, hemC Protein, pbg-d Protein, pbgd Protein, ups Protein, SPAC806.01 Protein, DDBDRAFT_0186148 Protein, DDBDRAFT_0231417 Protein, DDB_0186148 Protein, DDB_0231417 Protein, Hmbs Protein, NV50236 Protein, T25658 Protein, Ups Protein, Uros1 Protein, hmbs Protein, zgc:64128 Protein, hmbsl Protein, id:ibd5004 Protein, im:7140060 Protein, zgc:110690 Protein, hydroxymethylbilane synthase Protein, hydroxymethylbilane synthase S homeolog Protein, hydroxymethylbilane synthase L homeolog Protein, hydroxymethylbilane synthase (predicted) Protein, Hydroxymethylbilane synthase Protein, hydroxymethylbilane synthase a Protein, hydroxymethylbilane synthase, b Protein, HMBS Protein, Hmbs Protein, hmbs Protein, hmbs.2.S Protein, hmbs.L Protein, CNC02250 Protein, hem3 Protein, hemC Protein, Trad_0335 Protein, Plabr_2100 Protein, Sgly_3113 Protein, SMLT_RS19660 Protein, PMI_RS16580 Protein, hmbsa Protein, hmbsb Protein
    Background
    This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
    Molecular Weight
    37.5 kDa
    NCBI Accession
    NP_001019553
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