HNRNPM Protein (His tag)

Catalog No. ABIN2722937

Product Details

Target: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HNRNPM protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human hnRNP-M / HNRNPM (N-term HIS tag, transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Jagdeo, Dufour, Fung, Luo, Kleifeld, Overall, Jan: "Heterogeneous Nuclear Ribonucleoprotein M Facilitates Enterovirus Infection." in: Journal of virology, Vol. 89, Issue 14, pp. 7064-78, (2015) (PubMed).

Target Details

Target: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Alternative Name: Hnrnp-M,hnrnpm (HNRNPM Products)

Synonyms: HNRPM Protein, si:ch211-197g15.1 Protein, wu:fa10g07 Protein, wu:fa98b02 Protein, hnrpm Protein, CG9373 Protein, Dmel\\CG9373 Protein, Hrp59 Protein, cg9373 Protein, hnRNP M Protein, hrp59 Protein, p75 Protein, CEAR Protein, HNRNPM4 Protein, HNRPM4 Protein, HTGR1 Protein, NAGR1 Protein, 2610023M21Rik Protein, AA409009 Protein, Hnrpm Protein, mKIAA4193 Protein, Hnrpm4 Protein, heterogeneous nuclear ribonucleoprotein M Protein, Heterogeneous nuclear ribonucleoprotein M Protein, rumpelstiltskin Protein, HNRNPM Protein, hnrnpm Protein, hnrpm Protein, rump Protein, Hnrnpm Protein

Background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.

Molecular Weight: 73.4 kDa

NCBI Accession: NP_112480