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IDUA Protein (Myc-DYKDDDDK Tag)

IDUA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723286
  • Target See all IDUA Proteins
    IDUA (Iduronidase, alpha-L- (IDUA))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IDUA protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Alpha-L-iduronidase / IDUA protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product IDUA Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    IDUA (Iduronidase, alpha-L- (IDUA))
    Alternative Name
    Iduronidase, alpha-L (Idua) (IDUA Products)
    Synonyms
    IDA Protein, MPS1 Protein, 6030426D08 Protein, alpha-L-iduronidase Protein, MGC80842 Protein, si:ch211-12e13.9 Protein, IDUA Protein, iduronidase, alpha-L- Protein, iduronidase, alpha-L- L homeolog Protein, alpha-L-iduronidase Protein, IDUA Protein, Idua Protein, idua.L Protein, idua Protein, LOC5564727 Protein
    Background
    This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).
    Molecular Weight
    70 kDa
    NCBI Accession
    NP_000194
    Pathways
    Glycosaminoglycan Metabolic Process
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