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IL-37 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

IL37 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723380
  • Target See all IL-37 (IL37) Proteins
    IL-37 (IL37) (Interleukin 37 (IL37))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    Human
    Source
    • 8
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-37 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human IL1F7 / FIL1Z (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product IL37 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    IL-37 (IL37) (Interleukin 37 (IL37))
    Alternative Name
    Il1f7,fil1z (IL37 Products)
    Synonyms
    FIL1 Protein, FIL1(ZETA) Protein, FIL1Z Protein, IL-1F7 Protein, IL-1H Protein, IL-1H4 Protein, IL-1RP1 Protein, IL-37 Protein, IL1F7 Protein, IL1H4 Protein, IL1RP1 Protein, interleukin 37 Protein, IL37 Protein
    Background
    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Molecular Weight
    23.9 kDa
    NCBI Accession
    NP_055254
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