ILF2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723410

Product Details

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ILF2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ILF2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Alternative Name: Ilf2 (ILF2 Products)

Synonyms: nf45 Protein, pro3063 Protein, ILF2 Protein, wu:fb34h01 Protein, zgc:73084 Protein, zgc:77276 Protein, NF45 Protein, PRO3063 Protein, 6230405A16Rik Protein, TEG-267 Protein, Tex261 Protein, Tex267 Protein, interleukin enhancer binding factor 2 Protein, interleukin enhancer binding factor 2 L homeolog Protein, ilf2 Protein, ILF2 Protein, ilf2.L Protein, Ilf2 Protein

Background: The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

Molecular Weight: 42.9 kDa

NCBI Accession: NP_004506