INPP5E Protein (Myc-DYKDDDDK Tag)
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- Target See all INPP5E Proteins
- INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This INPP5E protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human INPP5E protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product INPP5E Protein
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Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (AA 1-644) protein (GST tag)
INPP5E Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (AA 1-641) protein (His tag)Crystallography grade INPP5E Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E) (AA 1-644) protein (His tag)Crystallography grade INPP5E Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))
- Alternative Name
- Inpp5e (INPP5E Products)
- Synonyms
- 1200002L24Rik Protein, 72kDa Protein, mKIAA0123 Protein, CORS1 Protein, CPD4 Protein, JBTS1 Protein, MORMS Protein, PPI5PIV Protein, PMPCA Protein, inositol polyphosphate-5-phosphatase E Protein, Inpp5e Protein, INPP5E Protein
- Background
- The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 70 kDa
- NCBI Accession
- NP_063945
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