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INSIG2 Protein (Myc-DYKDDDDK Tag)

INSIG2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723492
  • Target See all INSIG2 Proteins
    INSIG2 (Insulin Induced Gene 2 (INSIG2))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This INSIG2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human INSIG2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product INSIG2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    INSIG2 (Insulin Induced Gene 2 (INSIG2))
    Alternative Name
    Insig2 (INSIG2 Products)
    Synonyms
    MGC82156 Protein, INSIG-2 Protein, 2900053I11Rik Protein, C730043J18Rik Protein, Insig-2 Protein, insulin induced gene 2 Protein, insulin induced gene 2 L homeolog Protein, insig2 Protein, insig2.L Protein, INSIG2 Protein, Insig2 Protein
    Background
    The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
    Molecular Weight
    24.6 kDa
    NCBI Accession
    NP_057217
    Pathways
    ER-Nucleus Signaling
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