IRF5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all IRF5 Proteins
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IRF5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Interferon regulatory factor 5 (IRF5), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IRF5 Protein
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Interferon Regulatory Factor 5 (IRF5) (AA 176-240) protein (His tag)
IRF5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interferon Regulatory Factor 5 (IRF5) (AA 1-200) protein (His tag)IRF5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interferon Regulatory Factor 5 (IRF5) (AA 395-504) protein (GST tag)IRF5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 5 (IRF5) (AA 1-498) protein (GST tag)IRF5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 5 (IRF5) (AA 1-498) protein (His tag)Crystallography grade IRF5 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interferon Regulatory Factor 5 (IRF5) (AA 1-497) protein (His tag)Crystallography grade IRF5 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interferon Regulatory Factor 5 (IRF5) (AA 1-497), (full length) protein (His-SUMO Tag)IRF5 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women. ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 11, pp. 5327-36, (2015) (PubMed).
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: "Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women. ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 11, pp. 5327-36, (2015) (PubMed).
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- Target
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
- Abstract
- IRF5 Products
- Synonyms
- IRF5 Protein, irf5 Protein, SLEB10 Protein, AW491843 Protein, mirf5 Protein, im:7155364 Protein, zgc:76986 Protein, interferon regulatory factor 5 Protein, interferon regulatory factor 5 L homeolog Protein, IRF5 Protein, irf5 Protein, Irf5 Protein, irf5.L Protein
- Background
- This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
- Molecular Weight
- 56.5 kDa
- NCBI Accession
- NP_002191
- Pathways
- TLR Signaling, Autophagy
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