JMJD6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723937

Product Details

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This JMJD6 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human JMJD6 / PTDSR (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Lawrence, Conderino, Rieder: "Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: role of Jumonji C-domain containing protein 6 in RHA demethylation." in: Virology, Vol. 452-453, pp. 1-11, (2014) (PubMed).

Target Details

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Alternative Name: Jmjd6,ptdsr (JMJD6 Products)

Synonyms: Ptdsr Protein, PSR Protein, PTDSR Protein, PTDSR1 Protein, psr Protein, ptdsr Protein, zfpsr Protein, zgc:66264 Protein, 5730436I23Rik Protein, D11Ertd195e Protein, PtdSerR Protein, mKIAA0585 Protein, GB15204 Protein, jmjd6 Protein, cg5383 Protein, ptdsr1 Protein, arginine demethylase and lysine hydroxylase Protein, jumonji domain containing 6 Protein, bifunctional arginine demethylase and lysyl-hydroxylase PSR Protein, jmjC domain-containing protein 4 homolog Protein, phosphatidylserine receptor Protein, jumonji domain containing 6 S homeolog Protein, jumonji domain containing 6 L homeolog Protein, Jmjd6 Protein, JMJD6 Protein, jmjd6 Protein, LOC411069 Protein, LOC5577546 Protein, CpipJ_CPIJ004848 Protein, CpipJ_CPIJ019866 Protein, jmjd6.S Protein, jmjd6.L Protein

Background: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 46.3 kDa

NCBI Accession: NP_055982