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JUP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

JUP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723948
  • Target See all JUP Proteins
    JUP (Junction Plakoglobin (JUP))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This JUP protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Junction plakoglobin (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product JUP Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    JUP (Junction Plakoglobin (JUP))
    Alternative Name
    Junction Plakoglobin (JUP Products)
    Synonyms
    ARVD12 Protein, CTNNG Protein, DP3 Protein, DPIII Protein, PDGB Protein, PKGB Protein, arvd12 Protein, ctnng Protein, dp3 Protein, dpiii Protein, pdgb Protein, pkgb Protein, plak Protein, D930025P04Rik Protein, PG Protein, cb80 Protein, danPG Protein, fb11b06 Protein, jup Protein, wu:fb11b06 Protein, junction plakoglobin Protein, junction plakoglobin L homeolog Protein, Junction plakoglobin Protein, junction plakoglobin a Protein, junction plakoglobin S homeolog Protein, JUP Protein, Jup Protein, jup Protein, jup.L Protein, Tsp_06656 Protein, plak Protein, jupa Protein, jup.S Protein
    Background
    This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene however, not all transcripts have been fully described.
    Molecular Weight
    81.6 kDa
    NCBI Accession
    NP_002221
    Pathways
    Cell-Cell Junction Organization, Maintenance of Protein Location
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