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KCNJ6 Protein (Myc-DYKDDDDK Tag)

KCNJ6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724044
  • Target See all KCNJ6 Proteins
    KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This KCNJ6 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human KCNJ6 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KCNJ6 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))
    Alternative Name
    Kcnj6 (KCNJ6 Products)
    Synonyms
    kcnj6 Protein, BIR1 Protein, GIRK-2 Protein, GIRK2 Protein, KATP-2 Protein, KATP2 Protein, KCNJ7 Protein, KIR3.2 Protein, hiGIRK2 Protein, Kir3.2 Protein, weaver Protein, wv Protein, potassium voltage-gated channel subfamily J member 6 Protein, potassium channel, inwardly rectifying subfamily J, member 5 Protein, potassium inwardly-rectifying channel, subfamily J, member 6 Protein, KCNJ6 Protein, kcnj5 Protein, Kcnj6 Protein
    Background
    This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    48.3 kDa
    NCBI Accession
    NP_002231
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