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UVSSA/KIAA1530 Protein (Myc-DYKDDDDK Tag)

UVSSA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724212
  • Target See all UVSSA/KIAA1530 (UVSSA) Proteins
    UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This UVSSA/KIAA1530 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human KIAA1530 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product UVSSA Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
    Alternative Name
    Kiaa1530 (UVSSA Products)
    Synonyms
    KIAA1530 Protein, UVSS3 Protein, kiaa1530 Protein, 4933407H18Rik Protein, D330017J19Rik Protein, Kiaa1530 Protein, mKIAA1530 Protein, UV stimulated scaffold protein A Protein, UVSSA Protein, uvssa Protein, Uvssa Protein
    Background
    The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    80.4 kDa
    NCBI Accession
    NP_065945
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