KLF4 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724292

Product Details

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This KLF4 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human KLF4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

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Target Details

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: Klf4 (KLF4 Products)

Synonyms: EZF Protein, GKLF Protein, Gklf Protein, Zie Protein, KLF4 Protein, biklf Protein, biklf-A Protein, Kruppel like factor 4 Protein, Kruppel-like factor 4 (gut) Protein, Kruppel-like factor 4 Protein, Kruppel-like factor 4 (gut) L homeolog Protein, KLF4 Protein, Klf4 Protein, klf4 Protein, klf4.L Protein

Background: This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 49.9 kDa

NCBI Accession: NP_004226

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance