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KPNA6 Protein (Myc-DYKDDDDK Tag)

KPNA6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724408
  • Target See all KPNA6 Proteins
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This KPNA6 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human KPNA6 / Importin alpha-7 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KPNA6 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
    Alternative Name
    Kpna6,importin alpha-7 (KPNA6 Products)
    Synonyms
    IPOA7 Protein, Kpna5 Protein, NPI-2 Protein, KPNA7 Protein, karyopherin subunit alpha 6 Protein, karyopherin (importin) alpha 6 Protein, karyopherin alpha 6 (importin alpha 7) Protein, karyopherin alpha 6 (importin alpha 7) S homeolog Protein, KPNA6 Protein, Kpna6 Protein, kpna6.S Protein
    Background
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
    Molecular Weight
    59.8 kDa
    NCBI Accession
    NP_036448
    Pathways
    Protein targeting to Nucleus
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