KPNA6 Protein (Myc-DYKDDDDK Tag)
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- Target See all KPNA6 Proteins
- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KPNA6 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human KPNA6 / Importin alpha-7 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KPNA6 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))
- Alternative Name
- Kpna6,importin alpha-7 (KPNA6 Products)
- Synonyms
- IPOA7 Protein, Kpna5 Protein, NPI-2 Protein, KPNA7 Protein, karyopherin subunit alpha 6 Protein, karyopherin (importin) alpha 6 Protein, karyopherin alpha 6 (importin alpha 7) Protein, karyopherin alpha 6 (importin alpha 7) S homeolog Protein, KPNA6 Protein, Kpna6 Protein, kpna6.S Protein
- Background
- Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
- Molecular Weight
- 59.8 kDa
- NCBI Accession
- NP_036448
- Pathways
- Protein targeting to Nucleus
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