LIN28B Protein (His tag)
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- Target See all LIN28B Proteins
- LIN28B (Lin-28 Homolog B (LIN28B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LIN28B protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human LIN28B (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LIN28B Protein
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Lin-28 Homolog B (LIN28B) (AA 1-250) protein (Strep Tag)
Crystallography grade LIN28B Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Lin-28 Homolog B (LIN28B) (AA 1-247) protein (Strep Tag)Crystallography grade LIN28B Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 20 mM PB, pH 7.4.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- LIN28B (Lin-28 Homolog B (LIN28B))
- Alternative Name
- Lin28b (LIN28B Products)
- Synonyms
- csdd2 Protein, LIN-28 Protein, CSDD2 Protein, 2810403D23Rik Protein, D030047M17Rik Protein, Lin-28.2 Protein, lin-28 homolog B Protein, lin-28 homolog B S homeolog Protein, lin-28 homolog B (C. elegans) Protein, LIN28B Protein, lin28b Protein, lin28b.S Protein, Lin28b Protein
- Background
- The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3&apos UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.
- Molecular Weight
- 26.9 kDa
- NCBI Accession
- NP_001004317
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