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Lipase A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

LIPA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724769
  • Target See all Lipase A (LIPA) Proteins
    Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Lipase A protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human LIPA (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LIPA Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
    Alternative Name
    Lipa (LIPA Products)
    Synonyms
    cesd Protein, lal Protein, LIPA Protein, CESD Protein, LAL Protein, Chole Protein, Chole2 Protein, Lip1 Protein, AA960673 Protein, Lal Protein, Lip-1 Protein, lipase A, lysosomal acid type Protein, lipase A, lysosomal acid, cholesterol esterase Protein, lipase A, lysosomal acid, cholesterol esterase L homeolog Protein, lysosomal acid lipase A Protein, LIPA Protein, lipa Protein, lipa.L Protein, Lipa Protein
    Background
    Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    43 kDa
    NCBI Accession
    NP_000226
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