LRRC8A Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724948

Product Details

Target: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LRRC8A protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human LRRC8A (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Alternative Name: Lrrc8a (LRRC8A Products)

Synonyms: AGM5 Protein, LRRC8 Protein, Lrrc8 Protein, mKIAA1437 Protein, wu:fb18g12 Protein, wu:fi21b10 Protein, LLRC8A Protein, leucine rich repeat containing 8 VRAC subunit A Protein, leucine rich repeat containing 8A Protein, leucine rich repeat containing 8 VRAC subunit Aa Protein, leucine-rich repeat containing 8 family member A S homeolog Protein, leucine rich repeat containing 8 family member A Protein, LRRC8A Protein, Lrrc8a Protein, lrrc8aa Protein, lrrc8a.S Protein

Background: This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Molecular Weight: 94 kDa

NCBI Accession: NP_001120717