Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)
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- Target See all Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT) Proteins
- Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- Myc-DYKDDDDK Tag
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human LRTOMT / LRRC51 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LRTOMT Protein
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Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT) (AA 1-192) protein (Strep Tag)
Crystallography grade LRTOMT Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT) (AA 1-192) protein (Strep Tag)Crystallography grade LRTOMT Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT) (AA 1-291) protein (rho-1D4 tag)Crystallography grade LRTOMT Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT)
- Alternative Name
- Lrtomt,lrrc51 (LRTOMT Products)
- Synonyms
- DFNB63 Protein, LRRC51 Protein, Lrtomt Protein, RGD1561509 Protein, lrrp51 Protein, lrtomt Protein, zgc:153736 Protein, leucine rich transmembrane and O-methyltransferase domain containing Protein, leucine-rich repeat-containing protein 51 Protein, leucine rich repeat containing 51 Protein, LRTOMT Protein, LRRC51 Protein, Lrtomt Protein, lrrc51 Protein
- Background
- This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene.
- Molecular Weight
- 22 kDa
- NCBI Accession
- NP_660352
- Pathways
- Sensory Perception of Sound
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