LZTFL1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725086

Product Details

Target: LZTFL1 (Leucine Zipper Transcription Factor-Like 1 (LZTFL1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LZTFL1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human LZTFL1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LZTFL1 (Leucine Zipper Transcription Factor-Like 1 (LZTFL1))

Alternative Name: Lztfl1 (LZTFL1 Products)

Synonyms: lztfl1 Protein, MGC53120 Protein, LZTFL1 Protein, DKFZp469B0113 Protein, fb53f12 Protein, wu:fb53f12 Protein, zgc:56268 Protein, BBS17 Protein, 5530402H04Rik Protein, 6130400H19Rik Protein, AI414725 Protein, AW048545 Protein, leucine zipper transcription factor like 1 L homeolog Protein, leucine zipper transcription factor like 1 Protein, leucine zipper transcription factor-like 1 Protein, lztfl1.L Protein, LZTFL1 Protein, lztfl1 Protein, Lztfl1 Protein

Background: This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 34.4 kDa

NCBI Accession: NP_065080