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LZTS2 Protein (Myc-DYKDDDDK Tag)

LZTS2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2725089
  • Target See all LZTS2 Proteins
    LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LZTS2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human LZTS2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LZTS2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))
    Alternative Name
    Lzts2 (LZTS2 Products)
    Synonyms
    lapser1 Protein, MGC89253 Protein, si:dkey-250a11.1 Protein, LAPSER1 Protein, BC014695 Protein, mKIAA1813 Protein, Lapser1 Protein, leucine zipper, putative tumor suppressor 2 Protein, leucine zipper tumor suppressor 2 Protein, leucine zipper, putative tumor suppressor 2a Protein, leucine zipper, putative tumor suppressor 2 S homeolog Protein, lzts2 Protein, LZTS2 Protein, lzts2a Protein, Lzts2 Protein, lzts2.S Protein
    Background
    The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.
    Molecular Weight
    72.6 kDa
    NCBI Accession
    NP_115805
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