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MAL Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

MAL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2725234
  • Target See all MAL Proteins
    MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant A
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MAL protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MAL (transcript variant a) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MAL Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))
    Alternative Name
    Mal (MAL Products)
    Synonyms
    AI326936 Protein, Bp50 Protein, GP39 Protein, HIGM1 Protein, IGM Protein, IMD3 Protein, T-BAM Protein, TRAP Protein, Tnfrsf5 Protein, p50 Protein, Mpv17 Protein, Vip17 Protein, mal Protein, wyatt Protein, MALGENE Protein, im:7142606 Protein, zgc:112003 Protein, mal, T-cell differentiation protein Protein, CD40 antigen Protein, myelin and lymphocyte protein, T cell differentiation protein Protein, myelin and lymphocyte protein Protein, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog Protein, MAL Protein, Cd40 Protein, Mal Protein, LOC100135389 Protein, mal Protein, tirap.L Protein
    Background
    The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
    Molecular Weight
    16.5 kDa
    NCBI Accession
    NP_002362
    Pathways
    Asymmetric Protein Localization
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