SPG21 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all SPG21 Proteins
- SPG21 (Spastic Paraplegia 21 (SPG21))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPG21 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Maspardin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPG21 Protein
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Spastic Paraplegia 21 (SPG21) (AA 1-308) protein (His tag)
SPG21 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Spastic Paraplegia 21 (SPG21) (AA 1-308) protein (GST tag)SPG21 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Spastic Paraplegia 21 (SPG21) (AA 211-306) protein (GST tag)SPG21 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Spastic Paraplegia 21 (SPG21) protein (GST tag,His tag)SPG21 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
Spastic Paraplegia 21 (SPG21) (AA 1-308) protein (Strep Tag)Crystallography grade SPG21 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Spastic Paraplegia 21 (SPG21) (AA 1-308) protein (Strep Tag)Crystallography grade SPG21 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Spastic Paraplegia 21 (SPG21) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SPG21 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPG21 (Spastic Paraplegia 21 (SPG21))
- Alternative Name
- Maspardin (SPG21 Products)
- Synonyms
- ACP33 Protein, GL010 Protein, MAST Protein, BM-019 Protein, C78576 Protein, D9Wsu18e Protein, Maspardin Protein, wu:fd07h02 Protein, zgc:73091 Protein, SPG21, maspardin Protein, spastic paraplegia 21 (autosomal recessive, Mast syndrome) Protein, SPG21, maspardin S homeolog Protein, SPG21 Protein, Spg21 Protein, spg21.S Protein, spg21 Protein
- Background
- The protein encoded by this gene binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. Mutations in this gene are associated with autosomal recessive spastic paraplegia 21 (SPG21), also known as mast syndrome. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 34.8 kDa
- NCBI Accession
- NP_001121361
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