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MATK Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

MATK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2725549
  • Target See all MATK Proteins
    MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 5
    • 2
    • 2
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MATK protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MATK (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MATK Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
    Alternative Name
    Matk (MATK Products)
    Synonyms
    si:ch211-63j24.2 Protein, CHK Protein, CTK Protein, HHYLTK Protein, HYL Protein, HYLTK Protein, Lsk Protein, Ntk Protein, Batk Protein, megakaryocyte-associated tyrosine kinase Protein, zinc finger RNA binding protein 2 Protein, matk Protein, MATK Protein, Matk Protein, ZFR2 Protein
    Background
    The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
    Molecular Weight
    56.3 kDa
    NCBI Accession
    NP_647612
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