MGP Protein (His tag)
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- Target See all MGP Proteins
- MGP (Matrix Gla Protein (MGP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MGP protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Matrix Gla Protein (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MGP Protein
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Matrix Gla Protein (MGP) (AA 20-96) protein (His tag)
MGP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Matrix Gla Protein (MGP) (AA 1-103) protein (GST tag)MGP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Matrix Gla Protein (MGP) (AA 20-104) protein (His tag)Crystallography grade MGP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MGP (Matrix Gla Protein (MGP))
- Alternative Name
- Matrix Gla Protein (MGP Products)
- Synonyms
- MGLAP Protein, NTI Protein, Mglap Protein, mgp-A Protein, MGP Protein, LOC100136434 Protein, mgp Protein, matrix Gla protein Protein, matrix Gla protein L homeolog Protein, MGP Protein, Mgp Protein, mgp.L Protein, mgp Protein
- Background
- This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia.
- Molecular Weight
- 12.2 kDa
- NCBI Accession
- NP_000891
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