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Menin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

MEN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2725822
  • Target See all Menin (MEN1) Proteins
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Menin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Menin (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MEN1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Alternative Name
    Menin (MEN1 Products)
    Synonyms
    MEAI Protein, SCG2 Protein, menin Protein, meai Protein, scg2 Protein, AW045611 Protein, menin 1 Protein, menin 1 L homeolog Protein, multiple endocrine neoplasia I Protein, multiple endocrine neoplasia 1 Protein, MEN1 Protein, men1 Protein, men1.L Protein, Men1 Protein
    Background
    This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    67.3 kDa
    NCBI Accession
    NP_570711
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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