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MGEA5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

MGEA5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2725936
  • Target See all MGEA5 Proteins
    MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 7
    • 4
    • 3
    • 1
    Human
    Source
    • 10
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MGEA5 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MGEA5 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MGEA5 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Ding, Ping, Shi, Feng, Zheng, Song, Zhu: "Thiamet-G-mediated inhibition of O-GlcNAcase sensitizes human leukemia cells to microtubule-stabilizing agent paclitaxel." in: Biochemical and biophysical research communications, Vol. 453, Issue 3, pp. 392-7, (2014) (PubMed).

  • Target
    MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))
    Alternative Name
    Mgea5 (MGEA5 Products)
    Synonyms
    MEA5 Protein, NCOAT Protein, OGA Protein, 2810009A20Rik Protein, 4833427O07Rik Protein, 5830447M11Rik Protein, AA408215 Protein, Hy5 Protein, Ncoat Protein, mKIAA0679 Protein, O-GLCNACASE Protein, cytochrome c oxidase subunit VIc Protein, meningioma expressed antigen 5 (hyaluronidase) Protein, COX6C Protein, MGEA5 Protein, Mgea5 Protein
    Background
    The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].
    Molecular Weight
    102.7 kDa
    NCBI Accession
    NP_036347
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
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