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MID1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

MID1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726004
  • Target See all MID1 Proteins
    MID1 (Midline 1 (MID1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 3
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MID1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Midline-1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MID1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MID1 (Midline 1 (MID1))
    Alternative Name
    Midline-1 (MID1 Products)
    Synonyms
    BBBG1 Protein, FXY Protein, GBBB1 Protein, MIDIN Protein, OGS1 Protein, OS Protein, OSX Protein, RNF59 Protein, TRIM18 Protein, XPRF Protein, ZNFXY Protein, 61B3-R Protein, DXHXS1141 Protein, Fxy Protein, Trim18 Protein, Midline1 Protein, bbbg1 Protein, fxy Protein, gbbb1 Protein, midin Protein, ogs1 Protein, osx Protein, rnf59 Protein, trim18 Protein, xprf Protein, znfxy Protein, midline 1 Protein, midline 1 L homeolog Protein, MID1 Protein, Mid1 Protein, mid1 Protein, mid1.L Protein
    Background
    The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the &aposRING-B box-coiled coil&apos (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.
    Molecular Weight
    75.1 kDa
    NCBI Accession
    NP_000372
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