CCL23 Protein
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- Target See all CCL23 Proteins
- CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human MIP3 / CCL23 (transcript variant CKbeta8) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 98 % , as determined by Coomassie stained SDS-PAGE.
- Endotoxin Level
- Less than 0.01 ng per μg protein as determined by the LAL method.
- Biological Activity Comment
- Bioactivity was measured by its property to chemoattract THP-1 cells in a dose dependent manner.
- Top Product
- Discover our top product CCL23 Protein
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Chemokine (C-C Motif) Ligand 23 (CCL23) (Active) protein
CCL23 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 1-137) protein (GST tag)CCL23 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 22-120) protein (His tag)Crystallography grade CCL23 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 40-120) protein (His tag)Crystallography grade CCL23 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 43-120) protein (His tag)Crystallography grade CCL23 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 48-120) protein (His tag)Crystallography grade CCL23 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chemokine (C-C Motif) Ligand 23 (CCL23) (AA 51-120) protein (His tag)Crystallography grade CCL23 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Concentration
- > 50 μg/mL
- Buffer
- 1 x PBS
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))
- Alternative Name
- Mip3,ccl23 (CCL23 Products)
- Synonyms
- CK-BETA-8 Protein, CKb8 Protein, Ckb-8 Protein, Ckb-8-1 Protein, MIP-3 Protein, MIP3 Protein, MPIF-1 Protein, SCYA23 Protein, hmrp-2a Protein, C-C motif chemokine 23 Protein, C-C motif chemokine ligand 23 Protein, chemokine (C-C motif) ligand 23 Protein, LOC508666 Protein, CCL23 Protein
- Background
- This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.
- Molecular Weight
- 8.5 kDa
- NCBI Accession
- NP_665905
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