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MSH5 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

MSH5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726437
  • Target See all MSH5 Proteins
    MSH5 (MutS Homolog 5 (MSH5))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 4
    Origin
    • 3
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MSH5 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MSH5 (transcript variant 4) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MSH5 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MSH5 (MutS Homolog 5 (MSH5))
    Alternative Name
    Msh5 (MSH5 Products)
    Synonyms
    MSH5 Protein, G7 Protein, MUTSH5 Protein, NG23 Protein, Mut5 Protein, mutS homolog 5 Protein, mutS protein homolog 5 Protein, MSH (MutS Homolog) family Protein, MSH5 Protein, msh5 Protein, LOC100635155 Protein, Msh5 Protein, msh-5 Protein
    Background
    This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene.
    Molecular Weight
    92.7 kDa
    NCBI Accession
    NP_751898
    Pathways
    M Phase
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