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MTHFR Protein (Myc-DYKDDDDK Tag)

MTHFR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726510
  • Target See all MTHFR Proteins
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MTHFR protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MTHFR protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MTHFR Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    Alternative Name
    Mthfr (MTHFR Products)
    Synonyms
    DDBDRAFT_0204686 Protein, DDBDRAFT_0230137 Protein, DDB_0204686 Protein, DDB_0230137 Protein, AI323986 Protein, methylenetetrahydrofolate reductase (NAD(P)H) L homeolog Protein, methylenetetrahydrofolate reductase Protein, methylenetetrahydrofolate reductase (NAD(P)H) Protein, 5,10-methylenetetrahydrofolate reductase Protein, mthfr.L Protein, MTHFR Protein, mthfr Protein, metF Protein, DDB_G0279137 Protein, Mthfr Protein
    Background
    The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009].
    Molecular Weight
    74.4 kDa
    NCBI Accession
    NP_005948
    Pathways
    Methionine Biosynthetic Process
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