MTMR14 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726527

Product Details

Target: MTMR14 (Myotubularin Related Protein 14 (MTMR14))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MTMR14 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MTMR14 / C3orf29 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Papp, Kovács, Billes, Varga, Tarnóci, Hackler, Puskás, Liliom, Tárnok, Schlett, Borsy, Pádár, Kovács, Hegedűs, Juhász, Komlós, Erdős, Gulyás, Vellai: "AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects." in: Autophagy, Vol. 12, Issue 2, pp. 273-86, (2016) (PubMed).

Target Details

Target: MTMR14 (Myotubularin Related Protein 14 (MTMR14))

Alternative Name: Mtmr14,c3orf29 (MTMR14 Products)

Synonyms: fc14d11 Protein, wu:fc14d11 Protein, MGC131146 Protein, C3orf29 Protein, 1110061O04Rik Protein, AW553738 Protein, C76151 Protein, RGD1304842 Protein, jumpy Protein, myotubularin related protein 14 Protein, myotubularin-related protein 14 Protein, myotubularin related protein 14 S homeolog Protein, mtmr14 Protein, LOC703936 Protein, mtmr14.S Protein, MTMR14 Protein, Mtmr14 Protein

Background: This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.[provided by RefSeq, Apr 2010].

Molecular Weight: 59.9 kDa

NCBI Accession: NP_071930

Pathways: Inositol Metabolic Process