MYL12A Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726661

Product Details

Target: MYL12A (Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MYL12A protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MYL12A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MYL12A (Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))

Alternative Name: Myl12a (MYL12A Products)

Synonyms: MLCB Protein, MRCL3 Protein, MRLC3 Protein, MYL2B Protein, RGD1309537 Protein, Rlc-a Protein, myosin light chain 12A Protein, MYL12A Protein, Myl12a Protein

Background: This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014].

Molecular Weight: 19.6 kDa

NCBI Accession: NP_006462