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NAB2 Protein (Myc-DYKDDDDK Tag)

NAB2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726772
  • Target See all NAB2 Proteins
    NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This NAB2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human NAB2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NAB2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
    Alternative Name
    Nab2 (NAB2 Products)
    Synonyms
    mader Protein, AI451907 Protein, MADER Protein, NGFI-A binding protein 2 (EGR1 binding protein 2) Protein, Ngfi-A binding protein 2 Protein, NGFI-A binding protein 2 Protein, nab2 Protein, Nab2 Protein, NAB2 Protein
    Background
    This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
    Molecular Weight
    56.4 kDa
    NCBI Accession
    NP_005958
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