NRN1 Protein
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- Target See all NRN1 Proteins
- NRN1 (Neuritin 1 (NRN1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Neuritin protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by a cell proliferation using rat C6 cells. ED50 for this effect is 20.0-30.0 ng/ml.
- Top Product
- Discover our top product NRN1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NRN1 (Neuritin 1 (NRN1))
- Alternative Name
- Neuritin (NRN1 Products)
- Synonyms
- NRN Protein, dJ380B8.2 Protein, 0710008J23Rik Protein, Cpg15 Protein, Nrn Protein, neuritin Protein, nrn1 Protein, zgc:92828 Protein, NRN1 Protein, cpg15 Protein, nrn Protein, nrn1-a Protein, nrn1-b Protein, nrn1b Protein, neuritin 1 Protein, neuritin 1a Protein, neuritin 1 S homeolog Protein, neuritin 1 L homeolog Protein, NRN1 Protein, Nrn1 Protein, nrn1a Protein, nrn1 Protein, nrn1.S Protein, nrn1.L Protein
- Background
- This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 9.72 kDa
- NCBI Accession
- NP_057672
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