NUDT15 Protein (Myc-DYKDDDDK Tag)
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- Target See all NUDT15 Proteins
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NUDT15 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NUDT15 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NUDT15 Protein
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Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15) (AA 1-164) protein (Strep Tag)
Crystallography grade NUDT15 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15) (AA 1-170) protein (Strep Tag)Crystallography grade NUDT15 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
- Alternative Name
- Nudt15 (NUDT15 Products)
- Synonyms
- MTH2 Protein, RP11-90M2.1 Protein, 6530403O17 Protein, A730068G11Rik Protein, nudix hydrolase 15 Protein, nudix (nucleoside diphosphate linked moiety X)-type motif 15 Protein, NUDT15 Protein, Nudt15 Protein
- Background
- This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
- Molecular Weight
- 18.4 kDa
- NCBI Accession
- NP_060753
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