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P2RY12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

P2RY12 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728089
  • Target See all P2RY12 Proteins
    P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This P2RY12 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human P2RY12 / P2Y12 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product P2RY12 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
    Alternative Name
    p2ry12,p2y12 (P2RY12 Products)
    Synonyms
    2900079B22Rik Protein, 4921504D23Rik Protein, P2Y12 Protein, ADPG-R Protein, BDPLT8 Protein, HORK3 Protein, P2T(AC) Protein, P2Y(12)R Protein, P2Y(AC) Protein, P2Y(ADP) Protein, P2Y(cyc) Protein, SP1999 Protein, P2y12 Protein, purinergic receptor P2Y, G-protein coupled 12 Protein, purinergic receptor P2Y12 Protein, P2ry12 Protein, P2RY12 Protein
    Background
    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
    Molecular Weight
    39.3 kDa
    NCBI Accession
    NP_073625
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