PAK6 Protein (Transcript Variant 1)
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- Target See all PAK6 Proteins
- PAK6 (P21-Activated Kinase 6 (PAK6))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human PAK6 (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 90 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Specific activity was determined as 2,086 pmoles/min/μg, according to the Zlyte assay protocol
- Top Product
- Discover our top product PAK6 Protein
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P21-Activated Kinase 6 (PAK6) (AA 1-681) (Active) protein (GST tag)
PAK6 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
P21-Activated Kinase 6 (PAK6) (AA 385-680) (Active) proteinPAK6 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func Active
P21-Activated Kinase 6 (PAK6) (AA 1-681) (Active) protein (His-GST)PAK6 Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
P21-Activated Kinase 6 (PAK6) (AA 1-681) protein (GST tag)PAK6 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
P21-Activated Kinase 6 (PAK6) (AA 1-681) protein (Strep Tag)Crystallography grade PAK6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
P21-Activated Kinase 6 (PAK6) (AA 1-682) protein (Strep Tag)Crystallography grade PAK6 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PAK6 (P21-Activated Kinase 6 (PAK6))
- Alternative Name
- Pak6 (PAK6 Products)
- Synonyms
- PAK5 Protein, 4732456M09 Protein, pak6 Protein, si:ch211-158b22.3 Protein, p21 (RAC1) activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6 Protein, p21 protein (Cdc42/Rac)-activated kinase 6b Protein, PAK6 Protein, Pak6 Protein, pak6b Protein
- Background
- This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 34.2 kDa
- NCBI Accession
- NP_064553
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