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PANK1 Protein (Myc-DYKDDDDK Tag)

PANK1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728201
  • Target See all PANK1 Proteins
    PANK1 (Pantothenate Kinase 1 (PANK1))
    Protein Type
    Recombinant
    Origin
    • 5
    • 2
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PANK1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PANK1 / PANK (transcript variant alpha) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PANK1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PANK1 (Pantothenate Kinase 1 (PANK1))
    Alternative Name
    Pank1,pank (PANK1 Products)
    Synonyms
    PANK Protein, 4632412I06Rik Protein, 5430426F23Rik Protein, Pank Protein, Pank1a Protein, Pank1b Protein, panK1beta Protein, PANK1 Protein, im:7149302 Protein, wu:fb51a11 Protein, zgc:158746 Protein, ATCOAA Protein, ATPANK1 Protein, T13D8.31 Protein, T13D8_31 Protein, pantothenate kinase 1 Protein, DKFZp469J1021 Protein, fb79e08 Protein, zgc:63556 Protein, wu:fb79e08 Protein, pantothenate kinase 1 Protein, pantothenate kinase 1b Protein, pantothenate kinase 1a Protein, PANK1 Protein, Pank1 Protein, pank1b Protein, EHI_183060 Protein, pank1a Protein
    Background
    This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636).
    Molecular Weight
    64.2 kDa
    NCBI Accession
    NP_683878
    Pathways
    Ribonucleoside Biosynthetic Process
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