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HRPT2 Protein (Myc-DYKDDDDK Tag)

CDC73 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728223
  • Target See all HRPT2 (CDC73) Proteins
    HRPT2 (CDC73) (Parafibromin (CDC73))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This HRPT2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Parafibromin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CDC73 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    HRPT2 (CDC73) (Parafibromin (CDC73))
    Alternative Name
    Parafibromin (CDC73 Products)
    Synonyms
    C1orf28 Protein, HPTJT Protein, HRPT2 Protein, HYX Protein, 8430414L16Rik Protein, BC027756 Protein, C130030P16Rik Protein, C81219 Protein, Hrpt2 Protein, hrpt2 Protein, zgc:63956 Protein, MGC108428 Protein, cdc73 Protein, LOC100222932 Protein, cell division cycle 73 Protein, cell division cycle 73, Paf1/RNA polymerase II complex component Protein, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) Protein, parafibromin Protein, cell division cycle 73 S homeolog Protein, CDC73 Protein, Cdc73 Protein, cdc73 Protein, Tsp_03925 Protein, Tsp_04052 Protein, Tsp_04125 Protein, cdc73.S Protein
    Background
    This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3&apos mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
    Molecular Weight
    60.4 kDa
    NCBI Accession
    NP_078805
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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