PARN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all PARN Proteins
- PARN (Poly A Specific Ribonuclease (PARN))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PARN protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PARN (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PARN Protein
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Poly A Specific Ribonuclease (PARN) (AA 1-639) protein (GST tag)
PARN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Poly A Specific Ribonuclease (PARN) (AA 501-599) protein (GST tag)PARN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Poly A Specific Ribonuclease (PARN) (AA 1-639) protein (Strep Tag)Crystallography grade PARN Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Poly A Specific Ribonuclease (PARN) (AA 1-624) protein (Strep Tag)Crystallography grade PARN Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Poly A Specific Ribonuclease (PARN) (AA 1-639), (full length) protein (His tag)PARN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Poly A Specific Ribonuclease (PARN) (AA 1-639), (full length) protein (His tag)PARN Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PARN (Poly A Specific Ribonuclease (PARN))
- Alternative Name
- Parn (PARN Products)
- Synonyms
- parn-A Protein, xparn Protein, DAN Protein, RGD1565449 Protein, zgc:56067 Protein, 1200003I18Rik Protein, poly(A)-specific ribonuclease L homeolog Protein, poly(A)-specific ribonuclease Protein, poly(A)-specific ribonuclease (deadenylation nuclease) Protein, parn.L Protein, PARN Protein, Parn Protein, parn Protein
- Background
- The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 73.3 kDa
- NCBI Accession
- NP_002573
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